Introduction: Peripheral Vascular Disease (PVD) is a major cause of morbidity and is associated with Coronary Artery Disease (CAD). We aimed to perform Lower Limb PERFUSION SCAN (LLPS) in patients referred for MYOCARDIAL PERFUSION Imaging (MPI) and estimate prevalence of PVD in subgroups with normal and abnormal MPI results. We also compared quantitative indices of LLPS in patients with and without abnormal MPI results with semi-quantitative QPS indices.Methods: 120 patients referred for MPI entered the study. Exercise or dipyridamole infusion was used as stress modality. After 99mTc-MIBI injection at peak stress, whole body posterior views and planar images from thighs and calves were obtained. Gated MPI was done subsequently. Rest phase was performed the following day. LLPS was analyzed visually and quantitatively.Results: In patients with abnormal and normal MPI results, LLPS revealed 22.58% and 1.92% prevalence of PVD in exercise subgroup (P-Value=0.004) and 50.00% and 10.52% in dipyridamole subgroup (P-Value=0.013), respectively. Both of these different prevalence were statistically significant. In exercise subgroup, mean ranks of Stress Index (Is) for all lower limb regions were statistically significantly greater in patients with normal MPI result. Also, among patients who had ischemia in exercise-rest MPI, negative correlations were seen between Is and Rest Index (Ir) of all regions and QPS quantitative indices.Conclusion: LLPS with 99mTc-MIBI, combined with MPI is a feasible method to detect lower limbs ischemia, especially in patients with abnormal MPI results. Correlating quantitative indices of LLPS with MPI-QPS also reflect coexistence of CAD and PVD.

We present a female patient with atypical chest pain who was referred to our department for ischemia evaluation. 99mTc-MIBI MYOCARDIAL PERFUSION SCAN with dipyridamole stress was performed. Sub-diaphragmatic activity in the hepatic tissue and then in the bowel loops caused severe overlap on the inferior wall even on consecutive delayed images. Dipyridamole stress was repeated for the patient with 201Tl. The study was interpretable this time without any interfering sub-diaphragmatic activity.

Background: Purpose of study was to find correlation between segmental PERFUSION defects (SPD) and wall motion defects (WMD) on Gated MYOCARDIAL PERFUSION SPECT (G-MPS) in patients of coronary artery disease (CAD).Material and Methods: Consenting adult patients referred for G-MPS for CAD assessment were enrolled in the study belonging both genders. Patients underwent Two days rest-stress study using 20- 25mci Tc-99m MIBI injected intravenously. Imaging was performed at Seimens E-cam gamma camera.Data was analyzed using software SPSS version 17.0.Results: Of 28 patients, male to female ratio was 65% and 35%, with 21% above 50 years.42% had single risk factor, hypertension being highest and 48% with two or more risk factors. Mean LVEF on stress and rest was 59% and 55% respectively.20 segment analysis was used to analyze 560 segments. Stress showed 17%, 23%, 18.3%, 30%, 9.6% SPD and 17.9%, 24.3%, 19%, 29.6%, 10% WMD in the anterior, inferior, septal, lateral and apical part respectively with lateral wall showing higher number of abnormalities. Rest study showed 7.8%, 35.9%, 20.2% 20.2%, 13.4% SPD and 13%, 33%, 18%, 24%, 12% WMD in anterior, inferior, septal, lateral and apical part respectively with inferior wall showing higher number of abnormalities.Conclusion: The study shows that Chi-square correlative index was calculated to be as 0.05 at the confidence interval of 95% which is significant. CAD producing significant SPD on stress shows similar extent of WMD indicating a good correlation between PERFUSION and wall motion. The discordanceof SPD and WMD was observed in less than 5%, probably due to cardiomyopathy, stunning and attenuation artifacts. Thus we may conclude that G-MPS can be used reliably for evaluation of LV PERFUSION and wall motion.

Background: Coronary heart disease the most prevalent form of cardiovascular disease, results from the blockage of blood flow through arteries. The MYOCARDIAL PERFUSION SCAN (MPS) is considered a non-invasive method to assess the heart condition and provides valuable information, such as End Diastolic Volume (EDV), End Systolic Volume (ESV), Ejection Fraction (EF), Lung to Heart Ratio (LHR), and Transient Ischemic Dilatation (TID).Objective: This study aimed to investigate changes in gated heart SCAN parameters to diagnose patients, who are candidates for heart surgery.Material and Methods: In this descriptive cross-sectional study, 40 patients who are candidates for heart surgery were enrolled to evaluate the relation between the parameters of the gated heart SCAN and the amount of ischemic area of the heart. After SCANning the patients, TID, ESV, LHR, and EF and also the movements of the heart walls are examined and analyzed in these patients.Results: According to the results of the one-sample t-test showing a significant difference between the parameters, the results were within the normal range (P-value<0.0001). Additionally, all patients showed changes in cardiac output and wall movement issues. Conclusion: The evaluation of MYOCARDIAL PERFUSION SCAN (MPS) and gated heart SCAN parameters can provide an effective method for diagnosing patients who may require heart surgery.

BACKGROUND: Autonomic nervous system dysfunction in diabetic patients can result in an atypical presentation of cardiovascular disease that can be missed. We aimed to use single-photon emission computed tomography (SPECT) to assess cardiovascular disease (CAD) in diabetic patients with atypical pain to determine whether the pain above reflects the CAD. METHODS: Diabetic patients with atypical cardiac symptoms were referred to the SPECT department. Demographic data such as age, gender, diabetes status, and other underlying diseases were gathered. A MYOCARDIAL PERFUSION SCAN was then performed. The results were recorded to evaluate the risk of MYOCARDIAL ischemia and the degree of coronary artery involvement in a non-invasive manner. RESULTS: The study included 222 (177 female) subjects with mean ages of 63. 01±, 11. 62 and 59. 41±, 9. 19 in positive and negative SPECT, respectively. The most common symptoms were atypical chest pain (51. 8%), followed by shortness of breath (50. 5%), nausea, and syncope (0. 9%). Cardiac parameters, such as the summed stress score (SSS), summed rest score (SRS), total PERFUSION deficit in stress (TPD-s), total PERFUSION deficit in rest (TPD-r), were significantly higher in the group with coronary artery involvement (P<0. 001). However, ejection fraction (EF), end-diastolic volume (EDV), and end-systolic volumes (ESV) parameters were not (P=. 0. 328, 0. 351, and 0. 443, respectively). CONCLUSIONS: The mere presence of diabetes does not necessitate any additional diagnostic tests beyond those required for the general population, and it is possible to follow a diagnostic course similar to that of the general population.